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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

High Creatinine Levels and Polycystic Kidney Disease (PKD)

2013-03-26 14:01

Polycystic Kidney Disease (PKD) is an abnormal medical condition that can lead to high creatinine level. Elevated creatinine level has a special meaning for Polycystic Kidney Disease patients, because it can help to decide whether they need to start dialysis or not.

What is the normal creatinine level?

Creatinine is a by-product of normal muscle contractions, which finally becomes a chemical wastes and discharged out of our body by kidneys. For a healthy individual, creatinine level in blood keeps in the normal range: 0.5-1.3mg/dL (about 45-90umol/L).

How is Polycystic Kidney Disease related with high creatinine level?

Polycystic Kidney Disease elevates creatinine level in blood by impairing kidney function. Polycystic Kidney Disease can be simply called PKD and refers to an inherited illness condition in which kidneys are filled with different sizes of cysts. These cysts enlarge over time and when they enlarge to a certain size, they will oppress surrounding kidney tissues and make them unable in getting enough nutrition and oxygen. These kidney tissues become necrotic finally and kidney function decreases. We know kidneys are responsible for discharging excess creatinine out of our body and when kidney function is impaired, creatinine build up in the blood and thus cause high creatinine level.

At what creatinine level is dialysis required for PKD patients?

In theory, dialysis is required to purify blood when creatinine level increases to 5. However, as a matter of fact, many kidney failure patients do not start dialysis until their life is really threatened.

For Polycystic Kidney Disease patients with high creatinine level, whether dialysis is required depends on their illness condition. In general, if they have no obvious discomforts, they can live without dialysis. However, once complications like nausea, vomiting, heart failure, acidosis and pulmonary edema occurs and meanwhile these conditions can not be alleviated with oral medicines, dialysis will be urgently needed.

Creatinine is one of the toxins produced by our body and when it can not be discharged successfully by our kidney, it means at least one half of kidney function has been affected. Therefore, for Polycystic Kidney Disease patients who found they have high creatinine leve, they should be alert about their kidney function and try to protect residual kidney tissues from being damaged by means of shrinking kidney cysts.

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