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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Creatinine 2.5 in PKD: Should I Be Worried

2013-04-14 16:27

Should I be worried about creatinine 2.5 in PKD? I am afraid the answer is Yes. Creatinine 2.5 is beyond the normal range very much and for a PKD patient, it means kidney function has been affected seriously by kidney cysts. Under such a condition, kidney function keeps decreasing and creatinine level keeps increasing if left alone.

Creatinine level in blood is kept in a stable range 0.5-1.3mg/dl and it can be affected by many conditions like diet, physical exercises and medicines and so on. In PKD cases, creatinine level increases because of decreased kidney function, as kidneys are in charge of excess creatinine.

Creatinine level 2.5 is not serious enough for patients to start dialysis or do kidney transplant, but it indicate at least a half of kidney function has been affected. Our kidney is composed of more than two million of nephrons and has great compensatory ability which means kidney function is not affected only when a small group of kidney tissues are damaged. In early stage of PKD, excess creatinine can be discharged timely by residual kidney function, so creatinine level does not increase. Clinical experiments show creatinine level increases when a half of kidney function impaired. Therefore, for PKD patients whose creatinine level has increased to 2.5, they need to realize that their kidney function has been affected seriously and can not help to discharge all the toxins effectively any more.

Creatinine is just one of the toxins produce by our body. For PKD patients with creatinine 2.5, there are various toxins in their blood, and these toxins is a serious threatening to their internal organs. Therefore, increased creatinine level not only means large amounts of toxins in blood, but also imply patients are running high risk for various complications like cardiovascular disease, brain disease and gastrointestinal diseases and so on.

How to lower creatinine level effectively is a hot topic among PKD patients, because dialysis is needed when creatinine level increases to 5. Also once patients start dialysis, they can not stop it and need to do it repeatedly. Actually, dialysis is needed because kidney function is impaired and can not remove toxins effectively. Therefore, improving kidney function, instead of lowering creatinine level, should be the ultimate goal.

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