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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Creatinine and GFR to Measure Kidney Function

2013-08-15 16:31

Creatinine and GFR are two indexes of kidney function level. Generally, the higher serum creatinine level but the lower GFR value, the worsen kidney condition. Therefore, creatinine and GFR tests are often used to measure kidney function.

Creatinine and kidney function

Creatinine is discharged from the body by kidney, so creatinine builds up in the body along with kidney damage. However, our kidneys themselves have strong compensatory function. Therefore, in the early stage, kidneys can still keep the creatinine level stable through compensatory function, changing urine volume and content, and PH value even though kidney is damaged to sone extent. This is why people can live normally and healthily after donating one kidney.

When 50% of kidney function is lost, creatinine level will rise but not obviously. Only if 70% of kidney function is damaged can creatinine elevate visibly. The following is the link between creatinine and kidney function.

Creatinine is below 1.5mg/dl, kidney function above 90%;

Creatinine is 1.5-2.0 mg/dl, kidney function 60-89%;

Creatinine is 2.1-5.0 mg/dl, kidney function 30-59%;

Creatinine is 5.1-7.9 mg/dl, kidney function 15-29%;

Creatinine is above 8.0 mg/dl, kidney function below 15%.

Generally, once serum creatinine level is higher than 5.0 mg/dl, it means patients’ kidney disease has aggravated to early end stage, while 8.0 mg/dl of creatinine level means late end stage. However, creatinine level is also associated to patients’ nutrition and muscle condition. Therefore, creatinine level can’t be the most accurate index to reflect how well kidneys are functioning.

GFR and kidney function

Compared with creatinine level, GFR is more accurate to measure kidney function. Usually, the value of GFR almost equals to the level of kidney function. When GFR is below 15ml/min, it means patients’ illness condition has developed to end stage, in which dialysis or kidney transplant may be needed to consider.

If you have high creatinine leve or low GFR, be alert to your kidney condition. Accepting treatment timely is the best way to prevent your kidney function from losing.

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