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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Urinalysis and Polycystic Kidney Disease

2014-08-03 03:59

Urinalysis and Polycystic Kidney DiseaseIn general, people will be recommended to take a urine or blood test when they are being in the suspicion of have a kidney disease. Polycystic Kidney Disease (PKD) is a genetic disorder. In the early stages, people may not find that because the cysts are too small to be diagnosed. So, what are the significance of a urinalysis for Polycystic Kidney Disease?

As your know, the kidney is the producer of urine and is responsible for discharging wastes and toxins of in the body. If you have Polycystic Kidney Disease (PKD), your will see protein or blood (or both) in the urine when you do urinalysis. Why does it mean?

Protein in the urine

For a healthy people, the protein is a macromolecule, which cannot pass through the kidneys. The healthy kidney can filter some small molecular substances, and will hold the protein back. Polycystic Kidney Disease is characterized by a cluster cysts on the kidneys and the cysts will cause renal damage with the growth of them. When the kidneys are injured, the permeability of glomeruli becomes increased and then those proteins can be filtered by the damaged kidneys.

You cannot see protein in the urine with eye. Only with a microscope can you see the protein. However, there are some signs that can be the clues of proteinuria. For example, persistent bubbles in the urine, urgent urine, frequent urine, swelling, high blood pressure and regular thirst may reflect proteinuria.

Blood in the urine

Hematuria (blood in urine) has two types: Gross hematuria (you can see it by your eye) and microscope hematuria( it is only seen under a microscope). In fact, “blood” is red blood cells. The same with protein, red blood cells will not pass through the kidneys. With Polycystic Kidney Disease, the kidneys are damaged and red blood cells leak out. In additions, if the cyst ruptures, blood in the urine is likely to happen.

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