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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Can PKD Skip Generation

2013-04-25 15:46

Can PKD Skip GenerationCan PKD (Polycystic Kidney Disease) skip generation? As for this question, the answer depends on the exact type of PKD. Clinicaly, PKD is mainly divided into two types: ARPKD (Autosomal Recessive Polycystic Kidney Disease) and ADPKD (Autosomal Dominant Polycystic Kidney Disease).

Can ARPKD skip generation?

Compared with ADPKD, ARPKD is rare and also can be called infantile polycystic kidney disease. ARPKD usually occurs when patient is still a baby and is always accompanied by liver cyst. According to clinical statistic, about a half of ARPKD babies die of kidney failure and respiratory failure within several hours or several days after their birth.

ARPKD can skip generation, but sadly, seldom of them can live to their childhood stage or adolescence.

Can ADPKD skip generation?

ADPKD is a monogenic hereditary kidney disease and usually occurs when patients grow to their 20, so it also can be called adult polycystic kidney disease. Similar with ARPKD, ADPKD also cause kidney failure can liver cyst, but it needs a longer time to progress to kidney failure, so ADPKD patients can live a longer time compared with ARPKD.

ADPKD can skip generation. For people with one parent, they have 50% chance to develop this genetic problem and for people whose two parents are sufferers of ADPKD, they have 75% chance for this disease.

At present, there is no treatment for ADPKD, but with comprehensive precautionary measures, onset of illness condition can be delayed effectively. ADPKD progresses because enlarged and increasing kidney cysts damage surrounding kidney tissues and thus impair kidney function. Therefore, it is of great importance to stop kidney cysts from enlarging for patients. At present, only Chinese medicines like micro-Chinese medicines have been proven to be effective in shrinking kidney cyst. They are natural and cause no side effects, so it is suitable for both young patients and elder patients.

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