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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Life Span of Autosomal Recessive Polycystic Kidney Disease

2014-06-20 23:18

Life Span of Autosomal Recessive Polycystic Kidney DiseaseAutosomal Recessive Polycystic Kidney Disease (ARPKD) is an inherited disease, which is less common than Autosomal Dominant Polycystic Kidney Disease, the other type of PKD. ARPKD is known as a kind of kidney disease that affects infants. Life span of ARPKD is generally not so good.

How is ARPKD diagnosed?

The majority of infants with ARPKD show enlarged, cyst-filled kidneys within the first month of life. These cysts will impair the kidneys’ ability to filter waste from the body. About 50% of infants with the disease will also have an enlarged liver. These infants are often detectable through ultrasound before the child is born.

What are the symptoms of ARPKD?

A minority of people with ARPKD do not show symptoms of the disease until later in childhood or early in adulthood, with liver disease being the dominant symptom. When the kidney are further damaged, high blood pressure will occur. They are also prone to urinary tract infections, frequent urination, pain in the back or the sides. The disease usually affects the liver and spleen, resulting in low blood cell counts, varicose veins, and hemorrhoids.

What is the life span of ARPKD?

According to studies, between 23% and 30% of infants with ARPKD die hours or days after birth due to breathing difficulties. Of those who survive infancy, about 85% survive their first year of life, 82% survive to age 10, and 73% live past the age of 15. In one study, 42% of those who survived their first year lived to the age of 20.

More than half of children will develop kidney failure by the age of 10. Without dialysis or transplantation, the disease is often fatal.

Since ARPKD often affects infants, careful treatment should be taken into consideration. You can get some suggestions from us for free of charge. Best wishes!

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