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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

What Does a Declining GFR Mean With PKD

2014-07-30 02:52

What Does a Declining GFR Mean With PKDWhat does a declining GFR mean with PKD? Well, if you know what GFR means and what the effects of PKD on GFR, you will know the answer.

What does GFR mean?

GFR, the abbreviation of glomerular filtration rate, which is a indicator reflecting how your kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

What are the normal results of GFR

According to the National Kidney Foundation, normal results range from 90-120mL/min (1.73m2). Older people will have lower normal GFR levels, because GFR decreases with age.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

What does a declining GFR mean?

When the GFR declines, it means excessive wastes cannot be filtered, because your kidneys are damaged. In clinic, Chronic Kidney Disease (CKD) is divided into five stages according to GFR. Levels below 60 mL/min for 3 or more months are a sign of Chronic Kidney Disease. GFR result lower than 15 mL/min/1.73 m2 is a sign of kidney failure and requires immediate medical attention.

How does PKD lead to a declining GFR?

Polycystic Kidney Disease is a genetic disorder, which is characterized by multiple kidney cysts on the kidneys. Those cysts are growing and will cause kidney damage when it is large enough to compress renal tissues. Compression leads ischemia and anoxia in the kidneys. After a long term, the renal tissues are destroyed due to lack of blood and oxygen. The glomeruli will also be damaged. Now, you may have got the answer.

Polycystic Kidney Disease is a high risk of Kidney Failure. Without timely treatment, it will progress quickly. If you have any questions, please do not hesitate to ask us, and we are always happy to help you.

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