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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

High Blood Pressure Affect PKD Progression

2013-04-20 11:28

It seems there is no relationship between high blood pressure and PKD (Polycystic Kidney Disease) which is a genetic cystic kidney disorder and marked by countless fluid collection in kidney. Well, as a matter of fact, PKD can cause high blood pressure and what is more, high blood pressure affect PKD progression directly.

In PKD, blood pressure increases when lots of renin are produced because of serious kidney damaes. High renin level affect angiotension II level and make it increaes. Angiotensin II has ability of shrinking blood vessels and when large amounts of angiotensin II are produced, blood vessels get shrunk and high blood pressure occurs. In this light, high blood pressure can be regarded as one of the symptoms of PKD.

PKD is a gentic kidney disorder. Although it is a problem regarding kidney and marked by cysts in kidney, its progression can be affected by high blood pressure. Persistent high blood pressure damage renal blood vessels and make them sclerotic. When renal blood vessels are damaged, protein leak out and cause proteinuria. For PKD patients, their kidneys have been damaged and can not bear heavy burden. Kidney damages are caused more easily in such a case and with the increase of kidney damages, kidney disease progresses. In this light, having a tight control about blood pressure is very helpful for slowing down PKD progression.

Generally, with elevated blood pressure, PKD patients need to limit salt intake as salt is high in sodium. Damaged kidneys become incapable in discharging excess sodium which may pile up and cause high pressure in blood. Alos, high sodium level in blood can cause leakage of fluid among space of tissues, leading to swelling or edema. In clinic, different antihypertensive medicines like ACEI, ARBs (Angiotensin II receptor blockers), calcium channel blokers, and diuretics and so on. Wih different illness condition and causes of high blood pressure, PKD paients need to ake different medicines, so it is great for patients to consult their doctors in advance before tehy make any decision.

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