How Does Polycystic Kidney Disease Progress to Kidney Failure
Polycystic Kidney Disease (PKD) is a genetic disorder and is divided into five stages. About half of Polycystic Kidney Disease patients over 50 years old will develop into Kidney Failure, but most of them do not know the reasons. You can find the answer in this article.
Stage 1 Polycystic Kidney Disease: Emerging Stage
At this stage, kidney cysts are so small to be detected. No symptoms occur before 20 years old.
Stage 2 Polycystic Kidney Disease: Growth Stage
About between 30-40 years old, patients have enlarged kidney cysts that start to press renal tissues, especially renal tubules. Kidney function is mild damaged. Symptoms like high blood pressure and back pain may be seen.
Stage 3 Polycystic Kidney Disease: Enlarged Stage
When PKD patients are over 40, the kidney cysts grow fast (usually more than 4 cm). Kidney function is moderately damaged. More symptoms like back pain, proteinuria, hematuria, hypertension, high serum creatinine level and decreased GFR (glomerular filtration rate) occur.
Stage 4 Polycystic Kidney Disease: Burst Stage
Kidneys are surrounded by cysts. Some kidney cysts are so large that they may rupture due to some forces. Kidney function is severely damaged. Blood in urine and infection caused by kidney cyst rupture should be immediately treated.
Stage 5 Polycystic Kidney Disease: Kidney Failure
Large amounts of nephrons are damaged, and kidneys shrink with much smaller sizes than normal ones.