What Is The Pathophysiology Of Edema In Kidney Failure

2014-11-24 03:38

Kidney failure may contribute to the loss of protein in the urine and the development of edema. The pathophysiology of edema in kidney failure forms in patients for two reasons, such as a heavy loss of protein in the urine and impaired kidney function. Follow us to see the details.

1. Heavy loss of protein in the urine

Heavy loss of protein in the urine is related to Nephrotic Syndrome. This disease results in a reduction in the concentration of albumin in the blood. Albumin is responsible for maintaining blood volume in the blood vessels. Thus, a reduction of fluid in the blood vessels occurs. In this condition, kidneys indicates that there is depletion of blood volume and therefore, attempt to retain salt. As a result, fluids moves into the interstitial spaces, leading to pitting edema.

The treatment of fluid retention is to reduce the loss of protein into the urine and to limit salt in the diet. ACE inhibitors and angiotensin receptor blocker may be used to reduce the loss of protein in urine.

2. Impaired kidney function

Kidney failure patients will have impaired renal function. Edema in this condition forms due to a limitation in the kidneys’ ability to excrete sodium into the urine. Thus, patients with kidney failure from whatever cause will develop edema if their intake of sodium exceeds the ability of their kidneys to excrete the sodium. The more advanced the kidney failure, the greater the problem of salt retention is more likely to become.

Dialysis can regulate salt balance and can remove salt during the treatment. But it has no help for impaired kidney function. To alleviate edema from the root, we need to repair injured kidney and improve renal function. Micro-Chinese Medicine Osmotherapy can achieve this result. The active ingredients can come to the kidney lesion directly with the help of osmosis device. The medicines have functions of expanding blood vessels, preventing inflammation and coagulation, degrading extracellular matrix and improving blood circulation. All these help provide a favorable environment for restoring kidney damage. When kidney function is improved, its ability to excrete sodium will increase, thus edema will be relieved.

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