Will PKD Cause Muscle Tenderness And Fatigue

2014-10-13 03:41

Many patients with polycystic kidney disease (PKD) often complain they have muscle tenderness and fatigue. With the aggravation of PKD, these conditions may become more serious. Well then, is muscle tenderness and fatigue related with PKD?

In the early stage of PKD, cysts are very small and do not cause any symptoms. So if muscle tenderness and fatigue appear at this time, this may be caused by other conditions. However, if muscle tenderness and fatigue occurs in advanced PKD, impaired kidney is the underlying cause and declined renal function will occur. In this condition, basic kidney functions including cleansing blood, regulating blood pressure, maintaining electrolytes balance, producing urine and secreting EPO are damaged badly.

What will happen when renal function declines?

Enlarged kidney cysts can destroy kidney inherent kidney cells. Thus, kidneys fail to do the above basic functions properly. As a result, a series of complications happen easily. With diseased kidneys, kidneys fail to produce enough EPO, leading to anemia. Anemia will cause lack of vigor and strength. So fatigue and muscle tenderness will occur.

In addition, some other factors can also lead to muscle tenderness. Enlarged kidney cysts can do damages on glomeruli and renal tubular gradually, leading to loss of kidney filtration and reabsorption function. Thus, the imbalance between fluid and electrolyte such as low calcium and magnesium may occur and then muscle pain occurs. Moreover, medications used to treat PKD may also cause muscle cramps.

In summary, muscle tenderness and fatigue will be caused by PKD. The radical treatment for them is to shrink kidney cysts and reduce damages on kidneys as well as improving renal function. You can describe your medical condition to our online doctor, he or she will give you some helpful treatment suggestion.

Leave your problems here and you will get nephrologists' advice with free of charge!