Top 6 Symptoms of PKD

2014-03-06 14:39

Polycystic Kidney Disease (PKD) is a genetic disorder of kidney cyst which is full of fluid, meaning that there are large amounts of cysts in kidneys. Cyst can grow more and larger, which damages kidney tissues and other parts. In general, PKD has two major categories: Autosomal Dominant PKD (ADPKD) and Autosomal Recessive PKD (ARPKD). PKD has very bad effects on kidneys. Patients with PKD should get treatment in time. There are large quantities of symptoms of PKD, and here we will introduce top 6 symptoms for you.

1. Kidney enlargement

As cyst grows and increases, kidneys will swell and become larger. Progressions of enlargement differ from one to the other, so patients with PKD have two kidneys with different sizes. In the later period, abdomen can be occupied by kidneys. And kidneys are filled with cysts. Consequently, kidneys of patients with PKD are in irregular sizes.

2. Insufficient kidney function

As PKD develops With the lapse of time, kidney function will be insufficient eventually. Only a few patients with PKD have kidney failure in adolescence, and decreased kidney function doesn’t occur until at the age of 40 years on most occasions. When patients are 70 years old, about half of kidney function can still work.

3. Pain in renal area

Patients with PKD can have slight or sharp pain in waist and back. Walking too much and sitting for a long time can aggravate pain feelings. However, pain feelings can be alleviated when patients lie in bed.

4. Polycystic liver

Polycystic liver always follows PKD. Besides, there is cyst in pancreas and ovary on some occasions.

5. Blood in the urine

When blood vessels of cyst wall are broken, there will be blood in the urine. Blood in the urine is also called hematuresis in clinic, which is divided into gross hematuria and microscopic hematuria.

6. High blood pressure

Half of patients with PKD can have the symptom of high blood pressure, which is associated with activation of the renin - angiotensin aldosterone system. And cyst can suppress surrounding tissues of kidneys, leading to elevation of blood pressure.

The above all are top 6 symptoms of PKD. We hope it is helpful for you, if you want to know more information, please contact us directly.

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